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Only if the use of an infusional 5-FU regimen is not possible, should a prudent titration of capecitabine doses based on monitoring of toxicity and starting with the recommended reduced dose be considered.” 30 e When two different genetic variants are identified in one patient, they may be located on the same allele or on different alleles

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Mass spectrometry for detection of 4‐hydroxy‐trans‐2‐nonenal (HNE) adducts with peptides and proteins